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Rhim,Hyangshuk
ÀÓÇâ¼÷(¼¼Æ÷Á¶Á÷)
: ºÐÀڽŰæ»ý¹°ÇÐ
: Molecular Biology Molecular Neurobiology
: 3147-8401
: 3147-8604
: hrhim@catholic.ac.kr
:
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1991³â-1994³â Baylor College of Medicine Molecular Virology ¹Ú»ç
1983³â-1985³â Korea Advanced Institutes of Science and Technology (KAIST) Biological Science and Engineering ¼®»ç
1979³â-1983³â Pusan National University Chemistry Çлç
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2010³â - ÇöÀç °¡Å縯´ëÇб³ ÀÇ°ú´ëÇÐ Á¤±³¼ö
2005³â-2010³â °¡Å縯´ëÇб³ ÀÇ°ú´ëÇÐ ºÎ±³¼ö
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1997³â-2000³â °¡Å縯´ëÇб³ ÀÇ°ú´ëÇÐ ÀüÀÓ°­»ç
1995³â-1997³â NIH/NHGRI Post Doc.
1994³â-1995³â Baylor College of Medicine Post Doc.
1988³â-1991³â U. Alabama at Birmingham ¹Ú»çÀü °úÁ¤
1985³â-1988³â KIST, À¯Àü°øÇм¾ÅÍ ¿¬±¸¿ø
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1977³â - ÇöÀç Çѱ¹ºÐÀÚ¼¼Æ÷»ý¹°ÇÐȸ Á¤È¸¿ø
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▫ Spatially restricted hypopigmenation associated with an E dnrbs-modifying locus on mouse chromosome 10. Hyangshuk Rhim. Karen J. Dunn, Anna Aronzon, Susanna Mac, Mickie Cheng, M. Lynn Lamoreux, Shirley M. Tilghman, and William J. Pavan. Genome Research. 2000, 10 : 17-29


▫ Intracellular Abeta and C99 aggregates induce mitochondria-dependent cell death in human neuroglioma H4 cells through recruitment of the 20S proteasome subunit. Hyo-Jin Park, Sang-Soo Kim, Seongman Kang, Hyangshuk Rhim. Brain research. 2009, 1273 : 1-8



▫ The serine protease HtrA2/Omi cleaves Parkin and irreversibly inactivates its E3 ubiquitin ligase activity. Hye-Min Park, Goo-Young Kim, Min-Kyung Nam, Geun-Hye Seong, Chul Han, Kwang Chul Chung, Seongman Kang, Hyangshuk Rhim. Biochemical and biophysical research communications (BBRC). 2009, 387 : 537-542


▫ Beta-Amyloid precursor protein is a direct cleavage target of HtrA2 serine protease implications for the physiological function of HtrA2 in the mitochondria. Hyo-Jin Park, Sang-Soo Kim, Young-Mo Seong, Kyung-Hee Kim, Hui Gwan Goo, Eun Jin Yoon, Do Sik Min, Seongman Kang, and Hyangshuk Rhim. The journal of biological chemistry (JBC). 2006, 281 : 34277-34287


▫ Autocatalytic processing of HtrA2/Omi is essential for induction of caspase-dependent cell death through antagonizing XIAP. Young-Mo Seong, Ju-Youn Choi, Hyo-Jin Park, Ki-Joong Kim, Sang-Gun Ahn, Geun-Hye Seong, In-Kyung Kim, Seongman Kang, and Hyangshuk Rhim. The journal of biological chemistry. 2004, 279 : 37588-37596